https://onlinelibrary.wiley.com/doi/epdf/10.1002/mgg3.364

Genotype-phenotype investigation of 35 patients from 11 unrelated families with camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome.

*First report suggesting that symptoms worsen with age.


https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0043-120765

Camptodactyly-Arthropathy-Coxa Vara-Pericarditis Syndrome with Shoulder Joint Involvement: A Case Report with Literature Review.


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350503/pdf/MIRT-26-33.pdf

The Efficacy of Yttrium-90 Radiosynovectomy in Patients with Camptodactyly-Arthropathy-Coxa Vara-Pericarditis Syndrome.

*The first report of an attempted treatment indicated a radiotherapy was ineffective.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094128/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880819/pdf/12969_2016_Article_93.pdf

https://www.tandfonline.com/doi/abs/10.3109/03009742.2015.1085085?journalCode=irhe20

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0116237

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779395/pdf/JCIS-3-24.pdf

https://www.sciencedirect.com/science/article/pii/S0049017212002764?via%3Dihub

https://www.arthroplastyjournal.org/article/S0883-5403(12)00025-3/fulltext

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204095/pdf/main.pdf

https://link.springer.com/article/10.1007%2Fs11033-010-9949-9

https://www.ajronline.org/doi/full/10.2214/ajr.185.2.01850522

http://www.jbc.org/content/280/35/31325.full.pdf

https://www.jci.org/articles/view/22263/pdf

https://www.nature.com/articles/ng1199_319


Pathognomonic acetabular cysts in camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome.

*The first report suggesting CACP can present with cyst formation in the knee joint.


Protein-losing enteropathy in camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome.

*Documents extreme pericarditis causing severe protein deficiencies.


Camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome: a mimicker of juvenile idiopathic arthritis.


Anti-lubricin monoclonal antibodies created using lubricin-knockout mice immunodetect lubricin in several species and in patients with healthy and diseased joints.


Camptodactyly-arthropathy-coxa vara-pericarditis syndrome: important differential for juvenile idiopathic arthritis.

*One of several reports aiming to spread awareness about the common Juvenile Idiopathic Arthritis misdiagnosis.


Camptodactyly-arthropathy-coxavara-pericarditis syndrome in Saudi Arabia: clinical and molecular genetic findings in 22 patients.


Total hip arthroplasty in adolescents with severe hip arthropathy and dysplasia associated with camptodactyly-arthropathy-coxa vara-pericarditis syndrome.

*Description of successful hip replacements in adolescents.


Proteoglycan 4, a novel immunomodulatory factor, regulates parathyroid hormone actions on hematopoietic cells.


Lubricin: a novel potential biotherapeutic approaches for the treatment of osteoarthritis.


Camptodactyly-arthropathy-coxa vara-pericarditis syndrome versus juvenile idiopathic arthropathy.


Consequences of disease-causing mutations on lubricin protein synthesis, secretion, and post-translational processing.

*Use of antibodies to explore regions of lubricin protein needed for function.


The secreted glycoprotein lubricin protects cartilage surfaces and inhibits synovial cell overgrowth.


CACP, encoding a secreted proteoglycan, is mutated in camptodactyly-arthropathy-coxa vara-pericarditis syndrome.

*Landmark report linking CACP symptoms to the specific gene PRG4, and the protein lubricin.